HORDB

General Information

ID: hor004039
Uniprot ID: NA
Protein name: Pyrokinin-1
Gene name: NA
Organism: Zophobas atratus
Family: Pyrokinin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: LPHYPRL
Length: 7
Propeptide: NA
Signal peptide: NA
Modification: T7 Leucine amide
Glycosylation: NA
Mutagenesis: NA

Activity

Function: The modulation of muscle contractile activity
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004039_AF2.pdb

hor004039_ESM.pdb

Physical Information

Mass:	100227	Formula:	C43H66N12O9
Absent amino acids:	ACDEFGIKMNQSTVW	Common amino acids:	LP
pI:	9.35	Basic residues:	2
Polar residues:	1	Hydrophobic residues:	2
Hydrophobicity:	-65.71	Boman Index:	-988
Half-Life:	5.5 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	2 min	Aliphatic Index	111.43
Instability Index:	10571.43	Extinction Coefficient cystines:	1490
Absorbance 280nm:	248.33

Literature

PubMed ID: 21067424
Title: Identification of Myotropic Neuropeptides From the Brain and Corpus Cardiacum-Corpus Allatum Complex of the Beetle, Zophobas Atratus